Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MARS1 | P56192 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638493 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1645663 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL3883314 | 0.78 | SMN1; SMN2 (0.79) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1646858 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL3886464 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1645449 | 0.74 | KMT2A (0.51) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1645621 | 0.72 | L3MBTL1 (0.50) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL3886808 | 0.72 | L3MBTL1 (0.50) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1644594 | 0.72 | ALDH1A1 (0.54) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL4552896 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1THRBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | disclosed |