Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.70 |
| ▸ | PGR | P06401 | 5/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.70 |
| ▸ | AR | P10275 | 4/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16474135 | 0.93 | NR3C1 (0.81) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL16479355 | 0.92 | NR3C1 (0.67) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL16474140 | 0.92 | NR3C1 (0.66) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL16389382 | 0.90 | NR3C1 (0.86) | NR3C1PGRCYP3A4ARADORA3 | |
| Acetone SCHEMBL14645259 | 0.88 | NR3C1 (0.81) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL4284 | 0.88 | NR3C1 (0.83) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL16474139 | 0.87 | NR3C1 (0.72) | NR3C1PGRCYP3A4ARADORA3 | |
| Alcohol SCHEMBL9363106 | 0.87 | NR3C1 (0.81) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL11903930 | 0.87 | NR3C1 (0.76) | NR3C1PGRCYP3A4ARADORA3 | |
| SCHEMBL3365954 | 0.87 | NR3C1 (0.76) | NR3C1PGRCYP3A4ARADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200341-A1 | Method for the Production of Fluoromethyl Esters of Androstan-17 beta Carboxylic Acids | HOVIONE INTER LIMITED (CH) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200341-A1 | Method for the Production of Fluoromethyl Esters of Androstan-17 beta Carboxylic Acids | HSD17B2, HSD17B7, CYP17A1 | NR3C1 76/4885PGR 872/4885CYP3A4 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.