Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479408 | 0.95 | METAP1 (0.35) | LMNAMETAP1THRBSMN1; SMN2SIRT2 | |
| SCHEMBL16474341 | 0.89 | SIRT2 (0.34) | METAP1THRBSMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL15277648 | 0.89 | SIRT2 (0.37) | LMNAMETAP1SMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL13005296 | 0.88 | MAPT (0.42) | LMNATHRBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL15277649 | 0.88 | ALDH1A1 (0.36) | LMNAMETAP1SMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL16474343 | 0.88 | ALDH1A1 (0.34) | LMNASMN1; SMN2SIRT2SIRT1MAPT | |
| SCHEMBL16479410 | 0.86 | ALOX5 (0.39) | LMNAMETAP1SIRT2SIRT1MAPT | |
| SCHEMBL16474344 | 0.86 | SIRT2 (0.34) | LMNAMETAP1SMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL18961301 | 0.85 | ALDH1A1 (0.36) | LMNAMETAP1SMN1; SMN2SIRT2SIRT1 | |
| SCHEMBL18971203 | 0.85 | ALDH1A1 (0.39) | LMNAMETAP1SMN1; SMN2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102652-B2 | Dichroic-photochromic 2H-naphtho[1,2-b]pyran compounds and devices | ALPHAMICRON INCORPORATED (US) | 2015-08-11 | — | — | US | disclosed |
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | ALPHAMICRON INCORPORATED (US) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140197361-A1 | DICHROIC-PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRAN COMPOUNDS AND DEVICES | NR0B2, NR0B1, DHCR24 | LMNA 1838/4885METAP1 4382/4885THRB 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.