SCHEMBL16475813

SCHEMBL16475813

c1ccc(-c2cc(-c3ccccc3)cc(-c3nc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)ccc54)nc4ccccc34)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.43
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.43
HPGD P15428 3/20 0.43
ATM Q13315 3/20 0.43
MAPT P10636 3/20 0.43
NPSR1 Q6W5P4 1/20 0.43
LMNA P02545 2/20 0.40
PTGER4 P35408 1/20 0.38
MAPK1 P28482 2/20 0.37
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HTT P42858 2/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HSP90AA1 P07900 1/20 0.36
NPY5R Q15761 1/20 0.35
IL1R1 P14778 1/20 0.35
TSPO P30536 1/20 0.35
HDAC4 P56524 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15682541 0.97 ALDH1A1 (0.40) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL23903020 0.96 KDM4E (0.42) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL16475809 0.95 KDM4E (0.46) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL16706368 0.95 L3MBTL1 (0.43) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL15537274 0.95 L3MBTL1 (0.43) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL15615518 0.95 L3MBTL1 (0.43) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL15638499 0.95 KDM4E (0.48) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL15583014 0.95 KDM4E (0.48) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL22479831 0.95 KDM4E (0.48) L3MBTL1ALDH1A1KDM4EHPGDATM
SCHEMBL16475779 0.95 KDM4E (0.48) L3MBTL1ALDH1A1KDM4EHPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9287512-B2 Organic electroluminescent compounds, layers and organic electroluminescent device using the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-03-15 US disclosed
US-20150357583-A1 Novel Organic Electroluminescent Compounds, Layers and Organic Electroluminescent Device Using The Same DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2015-12-10 US disclosed
US-20150357583-A1 Novel Organic Electroluminescent Compounds, Layers and Organic Electroluminescent Device Using The Same DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2015-12-10 US disclosed
US-20150171346-A1 Novel Organic Electroluminescent Compounds and Organic Electroluminescent Device Using The Same ROHM & HAAS ELECT MAT (KR) 2015-06-18 US disclosed
US-20150171346-A1 Novel Organic Electroluminescent Compounds and Organic Electroluminescent Device Using The Same ROHM & HAAS ELECT MAT (KR) 2015-06-18 US disclosed
US-20140107338-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Rohm, and Haas Electronic Materials Korea Ltd. (KR) 2014-04-17 US disclosed
US-20140107338-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Rohm, and Haas Electronic Materials Korea Ltd. (KR) 2014-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150171346-A1 Novel Organic Electroluminescent Compounds and Organic Electroluminescent Device Using The Same OR10J3, VDAC2, KCNN2 L3MBTL1 910/4885ALDH1A1 590/4885KDM4E 826/4885
US-20140107338-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME OR10J3, VDAC2, KCNN2 L3MBTL1 910/4885ALDH1A1 590/4885KDM4E 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.