Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 9/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GALK1 | P51570 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | MPI | P34949 | 2/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908046 | 0.87 | ALDH1A1 (0.36) | HSF1SIRT1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15909984 | 0.86 | ALDH1A1 (0.36) | HSF1SIRT1KDM4EPOLBMAPT | |
| SCHEMBL15908038 | 0.82 | CYP1A2 (0.34) | KDM4EMAPTSMN1; SMN2HTTCASP6 | |
| SCHEMBL16476444 | 0.79 | KDM4E (0.40) | SIRT1KDM4EMAPTSMN1; SMN2L3MBTL1 | |
| Iodide SCHEMBL29959754 | 0.78 | KDM4E (0.39) | SIRT1KDM4EMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16479714 | 0.77 | KDM4E (0.46) | SIRT1KDM4EMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16476445 | 0.75 | KDM4E (0.37) | KDM4EPOLBMAPTSMN1; SMN2L3MBTL1 | |
| Iodide SCHEMBL17254509 | 0.74 | KDM4E (0.37) | KDM4EPOLBMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15908096 | 0.73 | KDM4E (0.41) | SIRT1KDM4EMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16476446 | 0.73 | KDM4E (0.43) | SIRT1TDP2KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723743-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2019-08-14 | — | — | EP | disclosed |
| WO-2017167992-A1 | PHOTOSENSITIVE DISPERSION AND USE THEREOF | UNIVERSITÄT REGENSBURG (DE) | 2017-10-05 | — | — | WO | disclosed |
| US-9185913-B2 | 10H-benzo[g]pteridine-2,4-dione derivatives, method for the production thereof, and use thereof | TRIOPTOTEC GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-20140200220-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200220-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | DHPS, DOHH, DPYD | HSF1 3248/4885SIRT1 238/4885TDP2 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.