Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27511682 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2GAASCN2A | |
| SCHEMBL23817578 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2GAASCN2A | |
| SCHEMBL73389 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2GAASCN2A | |
| SCHEMBL11333666 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2GAASCN2A | |
| SCHEMBL1991553 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4ESCN2ASCN8ASCN4A | |
| SCHEMBL15926506 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2GAASCN2A | |
| Ammonia Solution, Strong SCHEMBL8858388 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ESCN2ASCN8ASCN4A | |
| SCHEMBL27934690 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2GAASCN2A | |
| SCHEMBL24823151 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2GAASCN2A | |
| Hydrochloric Acid SCHEMBL28584097 | 0.79 | LMNA (0.50) | ALDH1A1KDM4ESCN2ASCN8ASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848614-A2 | Acrylamide derivatives as antibiotic agents | Debiopharm International SA (CH) | 2015-03-18 | — | — | EP | disclosed |
| US-20140107106-A1 | THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107106-A1 | THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME | MCL1, DHFR, ANXA5 | ALDH1A1 2015/4885KDM4E 4494/4885SMN1; SMN2 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.