Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817322 | 0.87 | FKBP1A (0.44) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19734038 | 0.84 | ALDH1A1 (0.44) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7864214 | 0.81 | FKBP1A (0.43) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21350707 | 0.80 | SMYD3 (0.41) | ALDH1A1TSHRPSEN1PSEN2APH1B | |
| SCHEMBL30621167 | 0.80 | PSEN1 (0.47) | ALDH1A1TSHRKMT2APSEN1PSEN2 | |
| SCHEMBL9893174 | 0.79 | TP53 (0.46) | ALDH1A1KDM4ETSHRCYP1A2KMT2A | |
| SCHEMBL4601664 | 0.78 | CASP3 (0.45) | — | |
| SCHEMBL28481811 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRCYP1A2KMT2A | |
| SCHEMBL9103351 | 0.77 | FKBP1A (0.47) | ALDH1A1KDM4ECYP1A2KMT2APOLB | |
| SCHEMBL9891874 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KDM4ECYP1A2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |