Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891824 | 0.81 | MAPT (0.53) | MAPTHPGDALDH1A1NPSR1LMNA | |
| SCHEMBL9893007 | 0.81 | MAPT (0.53) | MAPTHPGDALDH1A1NPSR1LMNA | |
| SCHEMBL1432868 | 0.80 | MAPT (0.38) | MAPTHPGDALDH1A1TP53KMT2A | |
| SCHEMBL16480419 | 0.76 | MAPT (0.52) | MAPTHPGDALDH1A1TP53KMT2A | |
| SCHEMBL23229431 | 0.73 | MAPT (1.00) | MAPTHPGDALDH1A1NPSR1LMNA | |
| SCHEMBL24415299 | 0.73 | MAPT (0.93) | MAPTHPGDALDH1A1NPSR1LMNA | |
| SCHEMBL12869178 | 0.72 | ALDH1A1 (1.00) | MAPTHPGDALDH1A1NPSR1LMNA | |
| SCHEMBL5970126 | 0.71 | MAPT (0.96) | MAPTHPGDALDH1A1NPSR1LMNA | |
| SCHEMBL24415315 | 0.70 | ALDH1A1 (0.72) | MAPTHPGDALDH1A1NPSR1LMNA | |
| SCHEMBL12618675 | 0.68 | ALDH1A1 (0.67) | MAPTHPGDALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |