Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432868 | 0.84 | MAPT (0.38) | MAPTALDH1A1KMT2ACHRM4AR | |
| SCHEMBL9891823 | 0.79 | MAPT (0.47) | MAPTALDH1A1KMT2ASRD5A1SRD5A2 | |
| SCHEMBL9893050 | 0.79 | MAPT (0.47) | MAPTALDH1A1KMT2ASRD5A1SRD5A2 | |
| SCHEMBL16480458 | 0.76 | MAPT (0.57) | MAPTALDH1A1KMT2ASRD5A1SRD5A2 | |
| SCHEMBL28790486 | 0.74 | MAPT (0.69) | MAPTALDH1A1KMT2ASRD5A1GAA | |
| SCHEMBL24421824 | 0.67 | MAPT (0.87) | MAPTALDH1A1KMT2ASRD5A1HPGD | |
| SCHEMBL14950848 | 0.67 | SMN1; SMN2 (0.34) | MAPTALDH1A1KMT2ACHRM4GAA | |
| SCHEMBL22606166 | 0.66 | ALDH1A1 (0.83) | MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL13695430 | 0.64 | PDK2 (0.47) | ALDH1A1CHRM4ARJAK3 | |
| SCHEMBL6435838 | 0.64 | SRD5A1 (0.48) | MAPTALDH1A1KMT2ASRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |