SCHEMBL1648209

SCHEMBL1648209

Clc1c(Cl)c(Cl)c(SSc2c(Br)cc(Br)cc2Br)c(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4637268 0.84 TSHR (0.45) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL1646979 0.81 NMT1 (0.35) CYP3A4
SCHEMBL1647345 0.80 CYP3A4 (0.30) CYP3A4
SCHEMBL1646794 0.79
SCHEMBL1648008 0.77 ALOX15 (0.34) TSHRTDP1
SCHEMBL1647441 0.76 CA1 (0.32) TDP1
SCHEMBL1648011 0.74
SCHEMBL224297 0.72 MEN1 (0.31) TSHR
SCHEMBL25259748 0.70 TDP1 (0.47) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL1648429 0.70 FBP1 (0.40) CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed