SCHEMBL1648429

SCHEMBL1648429

Clc1c(Cl)c(Cl)c(SSc2ccc(Br)cc2)c(Cl)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.40
CYP2A6 P11509 1/20 0.36
MAOA P21397 2/20 0.33
MAOB P27338 1/20 0.33
MAPT P10636 2/20 0.32
MAPK1 P28482 2/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
GAA P10253 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 2/20 0.31
HPGD P15428 1/20 0.31
MGLL Q99685 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1647126 0.81 FBP1 (0.42) FBP1CYP2A6MAOAMAOBMAPT
SCHEMBL224947 0.80 CYP2A6 (0.57) FBP1CYP2A6MAOAMAOBMAPT
SCHEMBL1646794 0.77
Water SCHEMBL28293836 0.77 CYP2A6 (0.53) FBP1CYP2A6MAOAMAOBMAPT
SCHEMBL3798472 0.76 HPGD (0.60) FBP1MAOAMAOBMAPTMAPK1
SCHEMBL27923318 0.76 FBP1 (0.42) FBP1CYP2A6MAOAMAOBMAPT
SCHEMBL1647481 0.75 MAOA (0.39) FBP1MAOAMAPTMAPK1CYP1A2
SCHEMBL1648011 0.72
SCHEMBL943735 0.72 ALDH1A1 (0.52) FBP1CYP2A6MAOAMAOBMAPT
SCHEMBL10899441 0.72 MAOA (0.56) FBP1CYP2A6MAOAMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed