SCHEMBL16482123

SCHEMBL16482123

c1cncc(-c2ccc(-n3c4ccc(-c5cccnc5)cc4c4cc(-c5cccnc5)ccc43)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP11B2 P19099 6/20 0.47
CYP11B1 P15538 5/20 0.47
CYP19A1 P11511 3/20 0.47
MKNK1 Q9BUB5 2/20 0.47
MKNK2 Q9HBH9 2/20 0.47
KIF11 P52732 1/20 0.47
CYP17A1 P05093 1/20 0.47
NR4A2 P43354 1/20 0.46
PIM1 P11309 2/20 0.46
CHEK1 O14757 1/20 0.46
AURKA O14965 1/20 0.46
DAPK3 O43293 1/20 0.46
JAK2 O60674 1/20 0.46
PRKD3 O94806 1/20 0.46
MAP4K4 O95819 1/20 0.46
PAK4 O96013 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11998170 0.93 CYP19A1 (0.45) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL16521310 0.93 KDM4E (0.46) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL18790308 0.92 KDM4E (0.49) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL19762218 0.92 KDM4E (0.49) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL16284631 0.91 CYP11B1 (0.54) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL11998178 0.89 KDM4E (0.46) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL15159278 0.89 CYP19A1 (0.44) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL23057379 0.88 L3MBTL1 (0.51) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL19654636 0.88 KDM4E (0.43) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2
SCHEMBL19763282 0.88 KDM4E (0.45) CYP2A6ALDH1A1CYP1A2CYP3A4CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10862048-B2 Organic electroluminescent device, thin luminous film, display apparatus, and lighting apparatus MERCK PATENT GMBH (DE) 2020-12-08 US disclosed
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160268516-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, LIGHT EMITTING DEVICE, AND LIGHT EMITTING MATERIAL Konica Minolta, Inc. (JP) 2016-09-15 US disclosed
US-20160268516-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, LIGHT EMITTING DEVICE, AND LIGHT EMITTING MATERIAL Konica Minolta, Inc. (JP) 2016-09-15 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
WO-2014057971-A1 ELECTROLUMINESCENCE ELEMENT コニカミノルタ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS LPO, L1CAM, EML4 CYP2A6 654/4885ALDH1A1 340/4885CYP1A2 338/4885
US-10862048-B2 Organic electroluminescent device, thin luminous film, display apparatus, and lighting apparatus LPO, L1CAM, EML4 CYP2A6 654/4885ALDH1A1 340/4885CYP1A2 338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.