SCHEMBL16482168

SCHEMBL16482168

c1cnc2c(c1)oc1ccc(-c3cc(-n4c5ccccc5c5ccccc54)cc(-n4c5ccccc5c5ccccc54)c3)cc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 3/20 0.36
NPC1 O15118 2/20 0.36
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
KDM4E B2RXH2 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
LMNA P02545 3/20 0.32
PDE4D Q08499 2/20 0.32
HSP90AA1 P07900 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18232788 0.92 KDM4E (0.36) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL18232778 0.91 KDM4E (0.38) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL18232933 0.91 KDM4E (0.38) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL18232954 0.91 KDM4E (0.38) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL18232955 0.91 KDM4E (0.38) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL18232952 0.91 KDM4E (0.38) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL18226858 0.91 PLA2G2A (0.38) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL18232945 0.91 PLA2G2A (0.36) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL15855207 0.91 PLA2G2A (0.38) KMT2AMEN1MAPTNPC1CASP3
SCHEMBL15855209 0.91 PLA2G2A (0.38) KMT2AMEN1MAPTNPC1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10862048-B2 Organic electroluminescent device, thin luminous film, display apparatus, and lighting apparatus MERCK PATENT GMBH (DE) 2020-12-08 US disclosed
US-20190189932-A1 TRANSPARENT ELECTRODE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2019-06-20 US disclosed
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160268516-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, LIGHT EMITTING DEVICE, AND LIGHT EMITTING MATERIAL Konica Minolta, Inc. (JP) 2016-09-15 US disclosed
US-20160268516-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, LIGHT EMITTING DEVICE, AND LIGHT EMITTING MATERIAL Konica Minolta, Inc. (JP) 2016-09-15 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-9040975-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2015-05-26 US disclosed
US-9040975-B2 Organic electroluminescence element, illumination device, and display device Konica Minolta, Inc. (JP) 2015-05-26 US disclosed
WO-2014057971-A1 ELECTROLUMINESCENCE ELEMENT コニカミノルタ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS LPO, L1CAM, EML4 KMT2A 2230/4885MEN1 3208/4885MAPT 563/4885
US-10862048-B2 Organic electroluminescent device, thin luminous film, display apparatus, and lighting apparatus LPO, L1CAM, EML4 KMT2A 2230/4885MEN1 3208/4885MAPT 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.