Octocrylene

Octocrylene

SCHEMBL16483

CCCCC(CC)COC(=O)C(C#N)=C(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
LMNA P02545 3/20 1.00
MAPK1 P28482 3/20 1.00
CYP3A4 P08684 3/20 0.54
CA2 P00918 1/20 0.54
PRSS1 P07477 2/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
TSHR P16473 3/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
RECQL P46063 1/20 0.38
CTSL P07711 1/20 0.37
CTSS P25774 1/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octocrylene SCHEMBL1769135 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL28123035 0.99 ALDH1A1 (0.98) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL19583477 0.98 ALDH1A1 (0.95) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL818975 0.97 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL8180706 0.97 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL13492185 0.96 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL14300480 0.95 ALDH1A1 (0.91) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL442480 0.94 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL16806267 0.94 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL9069191 0.94 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 40424 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144741-A1 NOVEL COMPOSITIONS DSM IP ASSETS B.V. (NL) 2026-05-28 US claimed
EP-4319884-B1 COSMETIC COMPOSITION COMPRISING HINOKITIOL UNILEVER IP HOLDINGS B V (NL) 2026-05-27 EP claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP claimed
EP-3357485-B1 SUNSCREEN COSMETIC SHISEIDO CO LTD (JP) 2026-05-27 EP claimed
CN-122075332-A Composition, preparation method thereof and sun-screening composition 2026-05-26 CN claimed
WO-2026104139-A1 SUNSCREEN WITH HECTORITE BEIERSDORF AG (DE) 2026-05-21 WO claimed
US-20260137615-A1 Anhydrous Sunscreen Compositions With enhanced Ultraviolet Protection ELC MAN LLC (US) 2026-05-21 US claimed
WO-2026104140-A1 GLYCERYL STEARATE EMULSIFIERS IN COSMETIC EMULSIONS BEIERSDORF AG (DE) 2026-05-21 WO claimed
US-20260137611-A1 NOVEL COMPOSITIONS DSM IP ASSETS B V (NL) 2026-05-21 US claimed
CN-122056817-A Oil-pearl type composition for skin and preparation method and application thereof 广州科思生物科技有限公司 2026-05-19 CN claimed
US-4686099-A Aerosol waterproof sunscreen compositions CHESEBROUGH-POND'S INC. 1987-08-11 US claimed
US-4683134-A HIGH VISCOSITY, GELS, ETHYL CELLULOSE, CROSSLINKED POLYACRYLIC ACID PALINCZAR VICTOR 1987-07-28 US claimed
US-4671955-A ETHYL HYDROXYETHYL CELLULOSE AND AN ULTRAVIOLET RADIATION ABSORBER PALINCZAR VICTOR 1987-06-09 US claimed
US-4525504-A 1,4-CYCLOHEXANDEICARBOXYLIC ACID AND 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL, UV AND HINDERED AMINE STABILIZERS EASTMAN KODAK COMPANY (US) 1985-06-25 US claimed
US-4524165-A 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND 1,4-CYCLOHEXANE DIOL MONOMERS; POLYALKYLENE GLCOLS; STABILIZER MIXTURE EASTMAN KODAK COMPANY (US) 1985-06-18 US claimed
US-4169005-A LAMINATING ADHESIVE, PLASTIC FILM, CURING THE TOP COAT CHAMPION INTERNATIONAL CORPORATION (US) 1979-09-25 US claimed
US-4093473-A Solar panel with UV absorber AMOCO/ENRON SOLAR 1978-06-06 US claimed
US-3961051-A INSECTICIDES HOFFMANN-LA ROCHE INC. (US) 1976-06-01 US claimed
US-3953650-A ELECTRICAL CONDUCTORS WESTERN ELECTRIC COMPANY, INC. (US) 1976-04-27 US claimed
US-3941908-A POLYVINYL CHLORIDE PLASTICIZED WITH PHTHALADEHYDE WESTERN ELECTRIC COMPANY, INC. (US) 1976-03-02 US claimed