Octocrylene

Octocrylene

SCHEMBL1769135

CCCCC(CC)COC(=O)C(C#N)=C(c1ccccc1)c1ccccc1.CCCCC(CC)COC(=O)C(C#N)=C(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
LMNA P02545 3/20 1.00
MAPK1 P28482 3/20 1.00
CYP3A4 P08684 3/20 0.54
CA2 P00918 1/20 0.54
PRSS1 P07477 2/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
TSHR P16473 3/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
RECQL P46063 1/20 0.38
CTSL P07711 1/20 0.37
CTSS P25774 1/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octocrylene SCHEMBL16483 1.00 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL28123035 0.99 ALDH1A1 (0.98) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL19583477 0.98 ALDH1A1 (0.95) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL818975 0.97 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL8180706 0.97 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL13492185 0.96 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL14300480 0.95 ALDH1A1 (0.91) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL442480 0.94 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL16806267 0.94 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL9069191 0.94 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4110747-B1 PROCESS FOR THE EFFICIENT PREPARATION OF (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2024-07-03 EP disclosed
US-20230295066-A1 Process for the Efficient Preparation of (Bio)-Alkanediols SYMRISE AG (DE) 2023-09-21 US disclosed
EP-4240314-A1 BIOBASED GLYCERYL HEPTANOATE ESTER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME Inolex Investment Corporation (US) 2023-09-13 EP disclosed
EP-4110747-A1 PROCESS FOR THE EFFICIENT PREPARATION OF (BIO)-ALKANEDIOLS Symrise AG (DE) 2023-01-04 EP disclosed
WO-2022122902-A1 PROCESS FOR THE EFFICIENT PREPARATION OF (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2022-06-16 WO disclosed
WO-2022098829-A1 BIOBASED GLYCERYL HEPTANOATE ESTER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME INOLEX INVESTMENT CORPORATION (US) 2022-05-12 WO disclosed
EP-3481365-A1 SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2019-05-15 EP disclosed
WO-2018007577-A1 SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2018-01-11 WO disclosed
EP-3229766-A1 SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2017-10-18 EP disclosed
EP-3169304-A1 SPRAYABLE SUNSCREEN COMPOSITION WITH OIL BEADS L'OREAL (FR) 2017-05-24 EP disclosed
WO-2011061144-A2 THE PRESENT INVENTION RELATES TO THE USE OF BETA-(1, 3)- BETA-(1, 4) GLUCAN WITH AN AVERAGE MOLECULAR WEIGHT OF FROM 5.000 TO 150.000 DA FOR THE INCREASE OF SYNTHESIS OF COLLAGEN BASF SE (DE) 2011-05-26 WO disclosed
US-7309481-B2 Natural sunlight photostable composition TANNING RESEARCH LABORATORIES, INC. (US) 2007-12-18 US disclosed
US-7285262-B2 Natural sunlight photostable composition TANNING RESEARCH LABORATORIES, INC. (US) 2007-10-23 US disclosed
WO-2006086354-A2 NATURAL SUNLIGHT PHOTOSTABLE COMPOSITION TANNING RESEARCH LABORATORIES, INC. (US) 2006-08-17 WO disclosed
US-20060177389-A1 Natural sunlight photostable composition EVEREADY BATTERY COMPANY, LLC 2006-08-10 US disclosed
WO-2006016975-A2 NATURAL SUNLIGHT PHOTOSTABLE COMPOSITION TANNING RESEARCH LABORATORIES, INC. (US) 2006-02-16 WO disclosed
US-20050025727-A1 Combination of avobenzone, octocrylene and oxybenzone; minimizes formation of harmful free radicals EVEREADY BATTERY COMPANY, LLC 2005-02-03 US disclosed
US-6069258-A SUNSCREEN AGENTS; PROTECTIVE COATINGS FOR SKIN BASF AKTIENGESELLSCHAFT (DE) 2000-05-30 US disclosed
US-6037487-A UNSATURATED AMINE AND CARBONYL-CONTAINING COMPOUNDS OF GIVEN FORMULA WITH HIGH ABSORPTION IN THE UV-A RANGE BASF AKTIENGESELLSCHAFT (DE) 2000-03-14 US disclosed
US-5968484-A APPLYING 2-ORGANOCARBONYLACRYLONITRILE DERIVATIVE AS SUNSCREEN AGENT BASF AKTIENGESELLSCHAFT (DE) 1999-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295066-A1 Process for the Efficient Preparation of (Bio)-Alkanediols ALKBH3, AKR1C2, AKR7A2 ALDH1A1 40/4885LMNA 2839/4885MAPK1 4362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.