Octocrylene

Octocrylene

SCHEMBL818975

CCCCC(CC)COC(=O)C(C#N)=C(c1ccccc1)c1ccccc1.CCOC(=O)C(C#N)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.93
LMNA P02545 3/20 0.93
MAPK1 P28482 3/20 0.93
CYP3A4 P08684 3/20 0.51
CA2 P00918 1/20 0.51
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
TSHR P16473 3/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
ATM Q13315 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP19A1 P11511 2/20 0.37
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octocrylene SCHEMBL16483 0.97 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL1769135 0.97 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL28123035 0.95 ALDH1A1 (0.98) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL19583477 0.94 ALDH1A1 (0.95) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL442480 0.94 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL9069191 0.94 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL8180706 0.93 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL13492185 0.93 ALDH1A1 (0.93) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL14300480 0.92 ALDH1A1 (0.91) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL9069193 0.91 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112203635-B Inorganic particle dispersion for cosmetic containing block copolymer 株式会社资生堂 2024-01-16 CN disclosed
US-9139941-B2 Sheet having high water vapor permeability DSM IP ASSETS B.V. (NL) 2015-09-22 US disclosed
CN-102665672-B Polymersome and process for producing same SHISEIDO CO LTD 2014-09-17 CN disclosed
US-8603533-B2 Polymersomes and production method thereof SHISEIDO COMPANY, LTD. (JP) 2013-12-10 US disclosed
EP-2508169-A1 POLYMERSOME AND PROCESS FOR PRODUCING SAME Shiseido Company, Ltd. (JP) 2012-10-10 EP disclosed
US-20120231055-A1 Polymersomes And Production Method Thereof SHISEIDO COMPANY, LTD. (JP) 2012-09-13 US disclosed
CN-102665672-A Polymersome and process for producing same SHISEIDO CO LTD 2012-09-12 CN disclosed
US-20110274905-A1 SHEET HAVING HIGH WATER VAPOR PERMEABILITY DSM IP ASSETS B.V. (NL) 2011-11-10 US disclosed