Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873954 | 0.96 | CYP1A2 (0.46) | CYP2A6CYP1A2BDKRB2SKP2IGF1R | |
| Ammonia Solution, Strong SCHEMBL27919205 | 0.96 | ESR1 (0.47) | CYP2A6CYP1A2BDKRB2ESR1ADRA2A | |
| Ammonia Solution, Strong SCHEMBL27937823 | 0.96 | ESR1 (0.47) | CYP2A6CYP1A2BDKRB2ESR1ADRA2A | |
| SCHEMBL3403193 | 0.94 | CYP2A6 (0.52) | CYP2A6CYP1A2BDKRB2SKP2IGF1R | |
| Ammonia Solution, Strong SCHEMBL27919258 | 0.92 | CYP2A6 (0.50) | CYP2A6CYP1A2BDKRB2SKP2IGF1R | |
| Ammonia Solution, Strong SCHEMBL27919143 | 0.91 | CYP1A2 (0.48) | CYP2A6CYP1A2ESR1ADRA2AADORA3 | |
| Ammonia Solution, Strong SCHEMBL27919155 | 0.91 | CYP1A2 (0.48) | CYP2A6CYP1A2ESR1ADRA2AADORA3 | |
| SCHEMBL6563401 | 0.90 | BDKRB2 (0.55) | BDKRB2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11695865 | 0.89 | CYP2A6 (0.54) | CYP2A6CYP1A2SKP2IGF1RALOX15 | |
| SCHEMBL11222681 | 0.88 | PTGS2 (0.57) | BDKRB2ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118080005-A | Application of cocatalyst in 2-methylnaphthalene acylation reaction | 品恩赢创(苏州)新材料科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117986101-A | Method for continuously synthesizing acyl naphthalene by coupling micromixer and reaction kettle | 品恩赢创(苏州)新材料科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-114369018-B | Method for continuously and synchronously rectifying acylation reaction liquid | 煤炭科学技术研究院有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-114349621-B | Method suitable for small continuous rectification of acylation reaction liquid | 煤炭科学技术研究院有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-115554914-A | Device and method for synthesizing 2-methyl-6-acylnaphthalene by continuous acylation | 大连理工大学 | 2023-01-03 | — | — | CN | claimed |
| CN-112876359-B | Preparation method of dimethyl 2, 6-naphthalene dicarboxylate | 上海中化科技有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-113292409-B | Method for separating high-purity 2-methyl-6-acylnaphthalene and 2-methyl-7-acylnaphthalene and application of rectification in method | 中化国际新材料(河北)有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-114369018-A | Method for continuously and synchronously rectifying acylation reaction liquid | 煤炭科学技术研究院有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114349621-A | Method suitable for small-sized continuous rectification of acylation reaction liquid | 煤炭科学技术研究院有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-113292409-A | Method for separating high-purity 2-methyl-6-acylnaphthalene and 2-methyl-7-acylnaphthalene and application of rectification in method | 中化国际新材料(河北)有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-112876359-A | Preparation method of dimethyl 2, 6-naphthalenedicarboxylate | 上海中化科技有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-108003007-A | A kind of preparation method of chemical intermediate 2,6- naphthalenedicarboxylic acids | 东莞市联洲知识产权运营管理有限公司 | 2018-05-08 | — | — | CN | claimed |
| CN-107879909-A | A kind of method using micro passage reaction synthesizing acyl naphthalene | 北京石油化工学院 | 2018-04-06 | — | — | CN | claimed |
| US-5138098-A | Catalytic actlation using complexing agent | AMOCO CORPORATION (US) | 1992-08-11 | — | — | US | claimed |
| US-5026917-A | Acetylation of 2-methylnaphthalenes | AMOCO CORPORATION (US) | 1991-06-25 | — | — | US | claimed |
| JP-3240751-A | — | — | None | — | — | JP | disclosed |
| CN-118304906-A | Combined catalyst for 2-methylnaphthalene acylation reaction and application thereof | 品恩赢创(苏州)新材料科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| US-5026917-A | Acetylation of 2-methylnaphthalenes | AMOCO CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| US-5026917-A | Acetylation of 2-methylnaphthalenes | AMOCO CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0203276-A1 | Process for the selective acylation of aromatic compounds | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1986-12-03 | — | — | EP | disclosed |