Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483593 | 0.92 | TNF (0.34) | TNFTOP2AMAPTDUSP3MAPK14 | |
| SCHEMBL16483600 | 0.92 | TNF (0.42) | TNFMAPTMAPK10MAPK14PIK3CD | |
| SCHEMBL16483613 | 0.90 | TNF (0.40) | TNFMAPTPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483317 | 0.89 | TNF (0.44) | TNFTOP2ADUSP3MAPK14PIK3CD | |
| SCHEMBL16483144 | 0.89 | TNF (0.41) | TNFTOP2AMAPTMAPK10PIK3CD | |
| SCHEMBL16483682 | 0.88 | TNF (0.42) | TNFTOP2AMAPTMAPK10PIK3CD | |
| SCHEMBL17341232 | 0.88 | ALDH1A1 (0.37) | MAPTDUSP3MAPK14CYP1A2 | |
| SCHEMBL16483161 | 0.86 | TNF (0.43) | TNFTOP2AMAPTMAPK10MAPK14 | |
| SCHEMBL16483591 | 0.86 | MAOA (0.40) | TNFTOP2AMAPTDUSP3MAPK14 | |
| SCHEMBL16483551 | 0.85 | TNF (0.43) | TNFTOP2AMAPTMAPK10PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |