Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483728 | 0.90 | KDM4E (0.35) | ALOX5TNFDYRK1AGSK3BKCNH2 | |
| SCHEMBL16484857 | 0.87 | TNF (0.39) | ALOX5TNFDYRK1AKCNH2 | |
| SCHEMBL16484885 | 0.86 | TNF (0.35) | ALOX5TNFDYRK1AGSK3BKCNH2 | |
| SCHEMBL16484912 | 0.85 | TNF (0.41) | ALOX5TNFDYRK1AGSK3BKCNH2 | |
| SCHEMBL16484870 | 0.85 | TNF (0.36) | ALOX5TNFDYRK1AGSK3BKCNH2 | |
| SCHEMBL16484909 | 0.84 | TNF (0.37) | ALOX5TNFDYRK1AGSK3BKCNH2 | |
| SCHEMBL10041356 | 0.84 | PGR (0.38) | DYRK1AKCNH2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL2628337 | 0.84 | PLA2G2A (0.37) | DYRK1APIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL16483433 | 0.83 | TNF (0.40) | ALOX5TNFDYRK1AKCNH2CDK2 | |
| SCHEMBL2628338 | 0.82 | BTK (0.38) | DYRK1AGSK3BKCNH2PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |