Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 9/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 10/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648408 | 0.81 | TMPRSS2 (0.63) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| SCHEMBL8544496 | 0.81 | TMPRSS2 (0.63) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| Guanisoquin SCHEMBL2109074 | 0.81 | TMPRSS2 (0.63) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| Debrisoquin SCHEMBL29390380 | 0.78 | TMPRSS2 (1.00) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| Debrisoquin SCHEMBL309184 | 0.78 | TMPRSS2 (1.00) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| Guanisoquin SCHEMBL29801607 | 0.75 | LMNA (0.68) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| Guanisoquin SCHEMBL121149 | 0.75 | LMNA (0.68) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| SCHEMBL22755532 | 0.74 | TMPRSS2 (0.63) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| SCHEMBL17902845 | 0.73 | TMPRSS2 (0.52) | TMPRSS2HTR1AADRA2ACYP2D6MAOA | |
| SCHEMBL24891975 | 0.72 | TMPRSS2 (0.80) | TMPRSS2HTR1AADRA2ACYP2D6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311810-A1 | AMIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2011-04-20 | — | — | EP | disclosed |