Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
| ▸ | HTR1D | P28221 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450201 | 0.74 | HTR5A (0.50) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL16484255 | 0.74 | NQO2 (0.38) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16484488 | 0.70 | IDO1 (0.46) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL24112590 | 0.69 | IDO1 (0.64) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL30310788 | 0.69 | IDO1 (0.64) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL8832651 | 0.66 | IDO1 (0.57) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL24019656 | 0.66 | HTR5A (0.45) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL24740178 | 0.66 | HTR5A (0.45) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL24112728 | 0.65 | HTR5A (0.51) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL24112229 | 0.65 | HTR5A (0.51) | HTR5AHTR1AHTR2CHTR7HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014058035-A1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2014-04-17 | — | — | WO | disclosed |