Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 8/20 | 0.50 |
| ▸ | HTR1A | P08908 | 6/20 | 0.50 |
| ▸ | HTR2C | P28335 | 6/20 | 0.50 |
| ▸ | HTR7 | P34969 | 6/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23835758 | 0.81 | PGR (0.43) | PGRCREBBPBRD4PBRM1L3MBTL1 | |
| SCHEMBL24450283 | 0.80 | PGR (0.43) | PGRCREBBPBRD4PBRM1MEN1 | |
| SCHEMBL24112728 | 0.79 | HTR5A (0.51) | HTR5AHTR1AHTR2CHTR7PGR | |
| SCHEMBL24112229 | 0.79 | HTR5A (0.51) | HTR5AHTR1AHTR2CHTR7PGR | |
| SCHEMBL24740178 | 0.76 | HTR5A (0.45) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL24019656 | 0.76 | HTR5A (0.45) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL24029073 | 0.75 | HTR5A (0.47) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL16484253 | 0.74 | HTR5A (0.37) | HTR5AHTR1AHTR2CHTR7PGR | |
| SCHEMBL24112590 | 0.74 | IDO1 (0.64) | HTR5AHTR1AHTR2CHTR7HTR1D | |
| SCHEMBL30310788 | 0.74 | IDO1 (0.64) | HTR5AHTR1AHTR2CHTR7HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162194-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162194-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTSV, CTRL, CTSL | HTR5A 4019/4885HTR1A 4514/4885HTR2C 1468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.