Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484522 | 0.77 | NQO2 (0.44) | NQO2CDYL2CDYLMEN1KMT2A | |
| SCHEMBL24019919 | 0.74 | PGR (0.57) | NQO2PGRMAPTTP53POLB | |
| SCHEMBL2988866 | 0.74 | PGR (0.57) | NQO2PGRMAPTTP53POLB | |
| SCHEMBL16484253 | 0.74 | HTR5A (0.37) | CDYL2CDYLMEN1KMT2APGR | |
| SCHEMBL16484488 | 0.71 | IDO1 (0.46) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL24113511 | 0.69 | IDO1 (0.67) | NQO2MEN1KMT2AATMPGR | |
| SCHEMBL30310572 | 0.69 | IDO1 (0.67) | NQO2MEN1KMT2AATMPGR | |
| SCHEMBL16484257 | 0.68 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL1455876 | 0.67 | HTR7 (0.47) | NQO2PGRMAPTTP53POLB | |
| SCHEMBL8832651 | 0.67 | IDO1 (0.57) | MEN1KMT2AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014058035-A1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2014-04-17 | — | — | WO | disclosed |