SCHEMBL16484333

SCHEMBL16484333

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc(N(c4ccccc4)c4ccncc4)c4cccc-3c24)cc1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ USP2 O75604 1/20 0.33
▸ TNF P01375 1/20 0.33
▸ NOTUM Q6P988 1/20 0.33
▸ TYMS P04818 2/20 0.32
▸ ENPP1 P22413 1/20 0.32
▸ MAPK14 Q16539 2/20 0.32
▸ IMPDH2 P12268 2/20 0.31
▸ POLB P06746 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ SLC6A2 P23975 1/20 0.30
▸ PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17012353 0.99 MEN1 (0.34) MEN1KMT2AUSP2TNFNOTUM
SCHEMBL17132486 0.93 TNF (0.35) MEN1KMT2AUSP2TNFKDM4E
SCHEMBL22113211 0.92 MEN1 (0.38) MEN1KMT2AUSP2ENPP1POLB
SCHEMBL17012357 0.90 TNF (0.39) MEN1KMT2AUSP2TNFTYMS
SCHEMBL12032220 0.89 MEN1 (0.38) MEN1KMT2AUSP2ENPP1POLB
SCHEMBL17132483 0.89 CYP11B1 (0.36) MEN1KMT2AUSP2TNFPOLB
SCHEMBL17012368 0.89 MAPT (0.35) TNFENPP1MAPK14MAPK1HSD17B10
SCHEMBL17132487 0.88 MEN1 (0.30) MEN1KMT2AUSP2MAPK14HPGD
SCHEMBL12032276 0.88 MEN1 (0.37) MEN1KMT2AUSP2ENPP1POLB
SCHEMBL17012354 0.87 ATM (0.33) MEN1KMT2AUSP2ENPP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 — — EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 — — EP disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 MEN1 553/4885KMT2A 298/4885USP2 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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