SCHEMBL17012368

SCHEMBL17012368

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc(N(c4ccncc4)c4ccc5ccccc5c4)c4cccc-3c24)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ TNF P01375 1/20 0.33
▸ SIRT2 Q8IXJ6 1/20 0.32
▸ MAPK8 P45983 1/20 0.32
▸ MAPK9 P45984 1/20 0.32
▸ MAPK10 P53779 1/20 0.32
▸ MAPK14 Q16539 2/20 0.31
▸ MAPK11 Q15759 1/20 0.31
▸ ESR1 P03372 2/20 0.31
▸ ESR2 Q92731 2/20 0.31
▸ LMNA P02545 2/20 0.31
▸ MAPK1 P28482 2/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ NPC1 O15118 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4076073 0.92 ESR1 (0.33) MAPTALDH1A1HPGDESR1ESR2
SCHEMBL17012353 0.90 MEN1 (0.34) MAPTALDH1A1KDM4EHPGDTNF
SCHEMBL16484473 0.89 TDO2 (0.38) TNFMAPK10
SCHEMBL16484478 0.89 TDO2 (0.38) TNFMAPK10
SCHEMBL16485322 0.89 TNF (0.39) MAPTALDH1A1KDM4EHPGDTNF
SCHEMBL16484333 0.89 MEN1 (0.33) MAPTALDH1A1KDM4EHPGDTNF
SCHEMBL17132489 0.89 CYP11B1 (0.37) MAPTALDH1A1KDM4EHPGDTNF
SCHEMBL16483997 0.88 TNF (0.35) MAPTALDH1A1KDM4EHPGDTNF
SCHEMBL16483971 0.87 ALDH1A1 (0.39) MAPTALDH1A1KDM4EHPGDMAPK8
SCHEMBL17012357 0.86 TNF (0.39) MAPTALDH1A1KDM4EHPGDTNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 — — EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 MAPT 937/4885ALDH1A1 1031/4885KDM4E 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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