SCHEMBL16484375

SCHEMBL16484375

c1ccc2cc3c(cc2c1)c1ccc2ccccc2c1n3-c1ccncc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 14/20 0.40
MAPK9 P45984 12/20 0.40
MAPK8 P45983 3/20 0.40
MEN1 O00255 1/20 0.36
HSP90AA1 P07900 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1B1 Q16678 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CFTR P13569 1/20 0.35
MAT2A P31153 1/20 0.35
ALDH1A1 P00352 2/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16484377 0.86 KDM4E (0.44) MAPK10MAPK9MAPK8MEN1HSP90AA1
SCHEMBL17123068 0.86 MAPT (0.42) MAPK10MAPK9MAPK8MEN1HSP90AA1
SCHEMBL18667686 0.82 MAPK10 (0.38) MAPK10MAPK9MAPK8MEN1HSP90AA1
SCHEMBL16484376 0.81 KDM4E (0.50) MAPK10MAPK9MAPK8MEN1HSP90AA1
SCHEMBL17989839 0.81 KDM4E (0.47) MAPK10MAPK9MAPK8MEN1HSP90AA1
SCHEMBL21863094 0.81 PDPK1 (0.38) MEN1MAPTKMT2ACYP1B1CYP1A1
SCHEMBL17132453 0.81 MAPT (0.37) MAPK10MAPK9MAPK8MEN1HSP90AA1
SCHEMBL22825667 0.80 PDPK1 (0.36) MAPK10MAPK9MAPK8MAPTCYP1B1
SCHEMBL23764125 0.80 MAT2A (0.32) MAPK10MAPK9MAPK8MEN1HSP90AA1
SCHEMBL24153008 0.80 PDPK1 (0.40) MAPK10MAPK9MAPK8MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 EP disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 MAPK10 2321/4885MAPK9 2958/4885MAPK8 2550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.