SCHEMBL16484694

SCHEMBL16484694

c1ccc(-n2c3ccccc3c3c4sc5c(ccc6c5c5ccccc5n6-c5ccccn5)c4ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ HTR7 P34969 1/20 0.35
▸ DPP4 P27487 1/20 0.33
▸ REN P00797 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ EP300 Q09472 1/20 0.33
▸ KAT2B Q92831 1/20 0.33
▸ RAB9A P51151 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ AVPR1A P37288 1/20 0.32
▸ KHK P50053 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17989805 0.88 KDM4E (0.49) KDM4EATML3MBTL1HTR7DPP4
SCHEMBL10027615 0.88 KDM4E (0.52) KDM4EATML3MBTL1HTR7DPP4
SCHEMBL16484649 0.88 KDM4E (0.34) KDM4EATML3MBTL1HTR7DPP4
SCHEMBL17108974 0.87 L3MBTL1 (0.36) KDM4EATML3MBTL1POLBRAB9A
SCHEMBL16484671 0.87 L3MBTL1 (0.45) KDM4EATML3MBTL1DPP4ALDH1A1
SCHEMBL11932984 0.86 L3MBTL1 (0.57) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL17246469 0.86 KMT2A (0.35) KDM4ERENALDH1A1POLBEP300
SCHEMBL16484686 0.85 KDM4E (0.42) KDM4EATML3MBTL1RENALDH1A1
SCHEMBL16484942 0.84 KDM4E (0.45) KDM4EATML3MBTL1HTR7DPP4
SCHEMBL17108959 0.84 KDM4E (0.45) KDM4EATML3MBTL1HTR7DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 — — US disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 — — US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 — — US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 — — US disclosed
WO-2014057684-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 出光興産株式会社 (JP) 2014-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME YBX1, ATXN2L, ATXN2 KDM4E 2405/4885ATM 3393/4885L3MBTL1 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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