SCHEMBL10027615

SCHEMBL10027615

c1ccc(-n2c3ccccc3c3c4c5ccccc5n(-c5ccccn5)c4ccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HTR7 P34969 1/20 0.40
POLB P06746 1/20 0.38
DPP4 P27487 1/20 0.38
REN P00797 1/20 0.37
ALDH1A1 P00352 1/20 0.37
RAB9A P51151 1/20 0.37
HTT P42858 1/20 0.36
AVPR1A P37288 1/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
FEN1 P39748 1/20 0.35
JAK2 O60674 1/20 0.35
JAK3 P52333 1/20 0.35
EP300 Q09472 1/20 0.35
KAT2B Q92831 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17248316 0.94 KDM4E (0.46) KDM4EATML3MBTL1HTR7POLB
SCHEMBL17989805 0.94 KDM4E (0.49) KDM4EATML3MBTL1HTR7POLB
SCHEMBL23805769 0.94 KDM4E (0.47) KDM4EATML3MBTL1HTR7POLB
SCHEMBL10027622 0.92 POLB (0.43) KDM4EATML3MBTL1POLBREN
SCHEMBL23805757 0.92 KDM4E (0.47) KDM4EATML3MBTL1HTR7POLB
SCHEMBL17989840 0.92 KDM4E (0.44) KDM4EATML3MBTL1HTR7POLB
SCHEMBL23805810 0.91 KDM4E (0.42) KDM4EATML3MBTL1POLBREN
SCHEMBL16999740 0.91 KDM4E (0.46) KDM4EATML3MBTL1HTR7POLB
SCHEMBL17108959 0.90 KDM4E (0.45) KDM4EATML3MBTL1HTR7POLB
SCHEMBL16484942 0.90 KDM4E (0.45) KDM4EATML3MBTL1HTR7POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702420-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-18 US disclosed
US-11322705-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-03 US disclosed
US-11088334-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-08-10 US disclosed
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-10573839-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-10305041-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-28 US disclosed
US-20190103562-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2019-04-04 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
EP-2416627-B1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL & SUMIKIN CHEM CO (JP) 2019-01-02 EP disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed
US-20150325801-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
EP-2933851-A1 ORGANIC ELECTRICAL FIELD LIGHT-EMITTING ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2015-10-21 EP disclosed
EP-2492987-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-08-29 EP disclosed
US-20120205640-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-08-16 US disclosed
US-20120205640-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-08-16 US disclosed
US-20120007070-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-12 US disclosed
US-20120007070-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11088334-B2 Organic electroluminescent element LEF1, AHR, OXA1L KDM4E 2743/4885ATM 3416/4885L3MBTL1 221/4885
US-11702420-B2 Organic electroluminescent materials and devices ECI1, NDUFS3, NDUFV1 KDM4E 3164/4885ATM 2475/4885L3MBTL1 2949/4885
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 KDM4E 1228/4885ATM 3768/4885L3MBTL1 74/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.