Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162272 | 0.79 | TSHR (0.50) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL2864499 | 0.78 | CES2 (0.39) | TSHRMEN1KMT2A | |
| SCHEMBL9729344 | 0.78 | CES2 (0.39) | TSHRMEN1KMT2A | |
| SCHEMBL7505879 | 0.78 | CES2 (0.39) | TSHRMEN1KMT2A | |
| SCHEMBL20875834 | 0.78 | CES2 (0.39) | TSHRMEN1KMT2A | |
| SCHEMBL8730946 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL21518299 | 0.74 | TSHR (0.54) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL6883385 | 0.73 | TSHR (0.52) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL9466416 | 0.73 | — | — | |
| SCHEMBL23559969 | 0.72 | TSHR (0.46) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906557-B1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-10-01 | — | — | US | disclosed |
| WO-2014058037-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, NOTUM, DDT | TSHR 3388/4885MEN1 1667/4885THRB 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.