Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421572 | 0.79 | ADRA1A (0.48) | ADRA1AHDAC11ALDH1A1 | |
| SCHEMBL10247191 | 0.76 | LMNA (0.42) | ADRA1AHDAC11ALDH1A1 | |
| SCHEMBL13458400 | 0.76 | CYP2C19 (0.48) | PAOXCASP2TRPA1 | |
| SCHEMBL4811015 | 0.74 | HDAC3 (0.43) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15187262 | 0.74 | MEN1 (0.63) | PAOXCASP2MAOAMAOBALDH1A1 | |
| SCHEMBL19861314 | 0.74 | MEN1 (0.42) | PAOXHDAC6CASP2HDAC3HDAC1 | |
| SCHEMBL19861326 | 0.74 | MEN1 (0.42) | PAOXHDAC6CASP2HDAC3HDAC1 | |
| SCHEMBL15187048 | 0.74 | MEN1 (0.63) | PAOXCASP2MAOAMAOBALDH1A1 | |
| SCHEMBL13534918 | 0.74 | KDM4A (0.42) | PAOXCASP2ADRA1APOLBPOLA1 | |
| SCHEMBL23945743 | 0.73 | PAOX (0.36) | PAOXHDAC6ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057687-A1 | ANTIBODY-DRUG CONJUGATE | 第一三共株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |