Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | DPP4 | P27487 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.69 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.69 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.69 |
| ▸ | GAPDH | P04406 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.69 |
| ▸ | STAT6 | P42226 | 1/20 | 0.69 |
| ▸ | PI4KA | P42356 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.69 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.69 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.69 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.69 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487371 | 0.94 | EHMT1 (0.71) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL17910030 | 0.93 | EHMT1 (0.73) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL9550940 | 0.92 | EGFR (0.62) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL17909992 | 0.90 | ADORA2A (0.66) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL6897965 | 0.88 | DOT1L (0.76) | KMT2ADOT1LEHMT1GNMTAHCY | |
| SCHEMBL26808204 | 0.88 | ADORA3 (0.67) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL26808295 | 0.88 | ADORA3 (0.67) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL1434130 | 0.87 | ADORA1 (0.67) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL10600555 | 0.86 | NNMT (0.69) | ADORA1ADORA3DPP4MEN1SLC28A1 | |
| SCHEMBL17909997 | 0.86 | ADORA1 (0.64) | ADORA1ADORA3DPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160201063-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160201063-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160201063-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | US | disclosed |
| EP-3033423-A1 | EPIGENETIC REGULATORS OF FRATAXIN | Rana Therapeutics Inc. (US) | 2016-06-22 | — | — | EP | disclosed |
| WO-2015023938-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2015-02-19 | — | — | WO | disclosed |
| WO-2015023938-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2015-02-19 | — | — | WO | disclosed |