Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.73 |
| ▸ | NNMT | P40261 | 1/20 | 0.69 |
| ▸ | GNMT | Q14749 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.65 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | DPP4 | P27487 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.65 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.65 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.65 |
| ▸ | GAPDH | P04406 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | STAT6 | P42226 | 1/20 | 0.65 |
| ▸ | PI4KA | P42356 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487371 | 0.97 | EHMT1 (0.71) | EHMT1NNMTGNMTADORA2AADORA1 | |
| SCHEMBL16486809 | 0.93 | ADORA1 (0.69) | EHMT1NNMTGNMTADORA2AADORA1 | |
| SCHEMBL13269089 | 0.88 | ADORA2A (0.64) | GNMTADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL6897965 | 0.85 | DOT1L (0.76) | EHMT1NNMTGNMTKMT2ADOT1L | |
| SCHEMBL9550940 | 0.85 | EGFR (0.62) | EHMT1GNMTADORA2AADORA1ADORA3 | |
| SCHEMBL1434130 | 0.84 | ADORA1 (0.67) | GNMTADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL16486895 | 0.84 | EHMT1 (1.00) | EHMT1NNMTADORA2AADORA1ADORA3 | |
| SCHEMBL10600555 | 0.84 | NNMT (0.69) | EHMT1NNMTADORA2AADORA1ADORA3 | |
| SCHEMBL14696727 | 0.84 | NNMT (0.78) | EHMT1NNMTGNMTADORA2AADORA1 | |
| SCHEMBL26808295 | 0.83 | ADORA3 (0.67) | GNMTADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160201063-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160201063-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160201063-A1 | EPIGENETIC REGULATORS OF FRATAXIN | RANA THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | US | disclosed |