Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487033 | 0.96 | MTNR1B (0.64) | MTNR1AMTNR1BPARP1HSD17B2L3MBTL1 | |
| SCHEMBL16486511 | 0.87 | MTNR1A (0.66) | MTNR1AMTNR1BPARP1 | |
| SCHEMBL16487029 | 0.86 | MTNR1B (0.47) | MTNR1AMTNR1BHSD17B2 | |
| SCHEMBL16487349 | 0.83 | MTNR1A (0.64) | MTNR1AMTNR1BPARP1 | |
| SCHEMBL16486780 | 0.82 | MTNR1A (0.60) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL3399533 | 0.75 | MTNR1B (1.00) | MTNR1AMTNR1B | |
| SCHEMBL16487090 | 0.75 | MTNR1B (0.59) | MTNR1AMTNR1BHSD17B2 | |
| SCHEMBL28382188 | 0.74 | PARP1 (0.56) | MTNR1AMTNR1BPARP1HSD17B2L3MBTL1 | |
| SCHEMBL24708886 | 0.74 | MTNR1B (0.62) | MTNR1AMTNR1BHSD17B2 | |
| SCHEMBL934349 | 0.74 | HDAC1 (0.63) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021535-A1 | METHODS AND USES OF MELATONIN LIGANDS | GOBBI GABRIELLA (CA) | 2015-02-19 | — | — | WO | claimed |
| WO-2015021535-A1 | METHODS AND USES OF MELATONIN LIGANDS | GOBBI GABRIELLA (CA) | 2015-02-19 | — | — | WO | disclosed |