Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486511 | 0.96 | MTNR1A (0.66) | MTNR1AMTNR1BPARP1 | |
| SCHEMBL20390462 | 0.88 | MTNR1A (0.63) | MTNR1AMTNR1BBCHEACHE | |
| SCHEMBL16487016 | 0.83 | MTNR1A (0.60) | MTNR1AMTNR1BPARP1 | |
| SCHEMBL16486913 | 0.80 | MTNR1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL16487033 | 0.80 | MTNR1B (0.64) | MTNR1AMTNR1BPARP1 | |
| SCHEMBL14149524 | 0.79 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL14352274 | 0.79 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL3397751 | 0.78 | MTNR1B (1.00) | MTNR1AMTNR1B | |
| SCHEMBL5535156 | 0.78 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL4516201 | 0.77 | MTNR1B (0.63) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021535-A1 | METHODS AND USES OF MELATONIN LIGANDS | GOBBI GABRIELLA (CA) | 2015-02-19 | — | — | WO | claimed |
| WO-2015021535-A1 | METHODS AND USES OF MELATONIN LIGANDS | GOBBI GABRIELLA (CA) | 2015-02-19 | — | — | WO | disclosed |