Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871725 | 0.85 | AURKA (0.38) | ESR1ESR2AURKADAPK3MAP4K4 | |
| SCHEMBL27947461 | 0.84 | ESR1 (0.38) | ESR1ESR2AURKADAPK3MAP4K4 | |
| SCHEMBL16487413 | 0.81 | HPRT1 (0.44) | AURKADAPK3MAP4K4RETIGF1R | |
| SCHEMBL11664492 | 0.81 | ESR1 (0.49) | ESR1ESR2AURKADAPK3MAP4K4 | |
| SCHEMBL8168399 | 0.80 | AKR1B1 (0.35) | ESR1ESR2AURKADAPK3MAP4K4 | |
| SCHEMBL7477557 | 0.79 | ALDH1A1 (0.36) | GABRA1GABRB2ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL2727987 | 0.79 | ESR1 (0.41) | ESR1ESR2ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL27763551 | 0.79 | ESR1 (0.41) | ESR1ESR2ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL6402798 | 0.78 | ALDH1A1 (0.35) | GABRA1GABRB2ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL27763603 | 0.78 | ESR1 (0.40) | ESR1ESR2ALDH1A1HIF1ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025109468-A1 | EMBEDDED CONTACT LENS WITH A HIGH REFRACTIVE INDEX INSERT THEREIN | ALCON INC. (CH) | 2025-05-30 | — | — | WO | disclosed |
| US-20250164823-A1 | EMBEDDED CONTACT LENS WITH A HIGH REFRACTIVE INDEX INSERT THEREIN | ALCON INC (CH) | 2025-05-22 | — | — | US | disclosed |
| EP-4314118-A1 | POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX | Alcon Inc. (CH) | 2024-02-07 | — | — | EP | disclosed |
| CN-116888193-A | Polysiloxane vinyl cross-linking agent with high refractive index | 爱尔康公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-105593234-A | Novel organopolysiloxane, surface treatment agent comprising the same, resin composition comprising the same, and gelatinous product or cured product thereof | DOW CORNING TORAY CO LTD | 2016-05-18 | — | — | CN | disclosed |
| WO-2015023001-A1 | NOVEL ORGANOPOLYSILOXANE, SURFACE TREATMENT AGENT COMPRISING THE SAME, RESIN COMPOSITION COMPRISING THE SAME, AND GELATINOUS PRODUCT OR CURED PRODUCT THEREOF | DOW CORNING TORAY CO., LTD. (JP) | 2015-02-19 | — | — | WO | disclosed |