SCHEMBL4871725

SCHEMBL4871725

C=CCc1ccc2ccccc2c1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.38
DAPK3 O43293 1/20 0.38
MAP4K4 O95819 1/20 0.38
RET P07949 1/20 0.38
IGF1R P08069 1/20 0.38
MET P08581 1/20 0.38
PIM1 P11309 1/20 0.38
LTK P29376 1/20 0.38
KDR P35968 1/20 0.38
MAPK8 P45983 1/20 0.38
MAPK9 P45984 1/20 0.38
CDK8 P49336 1/20 0.38
CLK2 P49760 1/20 0.38
CDK9 P50750 1/20 0.38
CDK5 Q00535 1/20 0.38
ACVR1 Q04771 1/20 0.38
PTK2 Q05397 1/20 0.38
MAP4K2 Q12851 1/20 0.38
IKBKE Q14164 1/20 0.38
LRRK2 Q5S007 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16487413 0.92 HPRT1 (0.44) AURKADAPK3MAP4K4RETIGF1R
SCHEMBL16487485 0.85 ESR1 (0.38) AURKADAPK3MAP4K4RETIGF1R
SCHEMBL16042131 0.81 GABRA1 (0.43) GABRA1ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL11664492 0.79 ESR1 (0.49) AURKADAPK3MAP4K4RETIGF1R
SCHEMBL7604074 0.78 WDR5 (0.46) GABRA1GABRG2GABRB3WDR5ALDH1A1
SCHEMBL299147 0.78 AURKA (0.38) AURKADAPK3MAP4K4RETIGF1R
SCHEMBL7556444 0.77 GABRA1 (0.48) AURKADAPK3MAP4K4RETIGF1R
SCHEMBL9275212 0.77 WDR5 (0.31) WDR5
SCHEMBL23581444 0.77 ALDH1A1 (0.38) GABRA1ALDH1A1CYP2A6TSHRHSD17B10
SCHEMBL253635 0.77 HSD17B10 (0.41) GABRA1ALDH1A1CYP2A6TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
WO-2025109468-A1 EMBEDDED CONTACT LENS WITH A HIGH REFRACTIVE INDEX INSERT THEREIN ALCON INC. (CH) 2025-05-30 WO disclosed
US-20250164823-A1 EMBEDDED CONTACT LENS WITH A HIGH REFRACTIVE INDEX INSERT THEREIN ALCON INC (CH) 2025-05-22 US disclosed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP disclosed
CN-116888193-A Polysiloxane vinyl cross-linking agent with high refractive index 爱尔康公司 2023-10-13 CN disclosed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO disclosed
CN-110423457-A A kind of novel low-cost vibration automatically cleaning shading Cooling window curtain plastics BENGBU CHUANGTE NEW MATERIAL TECH CO LTD 2019-11-08 CN disclosed
CN-105593234-B Novel organopolysiloxane, the surface conditioning agent comprising it, the resin combination comprising it and their gel-like product or cured product 道康宁东丽株式会社 2018-10-26 CN disclosed
CN-107810258-A Working fluid comprising fluorinated olefins and polyol ester 朗盛解决方案美国公司 2018-03-16 CN disclosed
CN-107353980-A A kind of high-temperature chain oil composition and preparation method thereof 合肥铭佑高温技术有限公司 2017-11-17 CN disclosed
CN-105593234-A Novel organopolysiloxane, surface treatment agent comprising the same, resin composition comprising the same, and gelatinous product or cured product thereof DOW CORNING TORAY CO LTD 2016-05-18 CN disclosed
WO-2015023001-A1 NOVEL ORGANOPOLYSILOXANE, SURFACE TREATMENT AGENT COMPRISING THE SAME, RESIN COMPOSITION COMPRISING THE SAME, AND GELATINOUS PRODUCT OR CURED PRODUCT THEREOF DOW CORNING TORAY CO., LTD. (JP) 2015-02-19 WO disclosed
US-7370957-B2 Ink jet recording apparatus FUJI XEROX CO., LTD. (JP) 2008-05-13 US disclosed
US-20060055757-A1 Ink jet recording apparatus FUJI XEROX CO., LTD. 2006-03-16 US disclosed
EP-1634713-A1 Ink jet recording apparatus FUJI XEROX CO., LTD. (JP) 2006-03-15 EP disclosed
JP-2000063304-A ALKYL (PHENYL) NAPHTHALENE DERIVATIVE AND ITS PRODUCTION DAINIPPON INK & CHEM INC 2000-02-29 JP disclosed