SCHEMBL7477557

SCHEMBL7477557

C=CCc1ccc2cc3ccccc3cc2c1CC=C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 3/20 0.36
HIF1A Q16665 2/20 0.36
CYP1B1 Q16678 1/20 0.36
HTR2A P28223 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
IMPDH2 P12268 1/20 0.33
SRD5A1 P18405 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPT P10636 2/20 0.32
PKM P14618 2/20 0.32
MAPK1 P28482 2/20 0.32
CYP3A4 P08684 2/20 0.32
ALOX15 P16050 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL253635 0.84 HSD17B10 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1GABRA1
SCHEMBL8637918 0.82 HSD17B10 (0.40) ALDH1A1HSD17B10HIF1ACYP1B1GABRA1
SCHEMBL6402798 0.81 ALDH1A1 (0.35) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL28826002 0.81 SRD5A1 (0.45) ALDH1A1HSD17B10HIF1AGABRA1GABRB2
SCHEMBL28242289 0.81 ALDH1A1 (0.37) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL4084762 0.81 ALDH1A1 (0.36) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
Anthracene SCHEMBL28476048 0.80 GABRA1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL729990 0.80 GABRA1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL30083979 0.80 GABRA1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1
SCHEMBL3806608 0.79 IMPDH2 (0.36) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME JSI SILICONE CO. (KR) 2021-06-24 US disclosed
CN-1798457-A Lighting apparatus TOYOTA JIDOSHOKKI KK (JP) 2006-07-05 CN disclosed
US-6361885-B1 ANODES AND CATHODES FOR ELECTROLUMINESCENT DEVICE ORGANIC DISPLAY TECHNOLOGY 2002-03-26 US disclosed
US-6344284-B1 ORGANO-SILOXANE (CARBOSILANE) POLYMER HAVING A MAIN CHAIN COMPRISING ANTHRACENE AND/OR PENTACENE OPTIONALLY DOPED WITH A PORPHYRIN, AN AROMATIC TERTIARY AMINE OR A DYE ORGANIC DISPLAY TECHNOLOGY 2002-02-05 US disclosed
US-6165383-A Useful precursors for organic electroluminescent materials and devices made from such materials ORGANIC DISPLAY TECHNOLOGY (US) 2000-12-26 US disclosed
WO-2000031208-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORGANIC DISPLAY TECHNOLOGY (US) 2000-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210188739-A1 METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME PFAS, FRK, AGPAT2 ALDH1A1 676/4885HSD17B10 1306/4885HIF1A 2300/4885
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 ALDH1A1 676/4885HSD17B10 1306/4885HIF1A 2300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.