Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL742952 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BNOTUMKDM4ECYP2C19 | |
| Hydrochloric Acid SCHEMBL3319271 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BNOTUMKDM4ECYP2C19 | |
| Trifluoroacetic Acid SCHEMBL1456945 | 0.85 | DPP4 (0.59) | ITGB3ITGA2BNOTUMDPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL6066398 | 0.82 | DPP4 (0.53) | ITGB3ITGA2BDPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL1025272 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BDPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL6066623 | 0.82 | DPP4 (0.53) | ITGB3ITGA2BDPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL1456260 | 0.82 | DPP4 (0.53) | ITGB3ITGA2BDPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL6986818 | 0.81 | CHKA (0.63) | DPP4DPP8DPP9DPP7CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL4716561 | 0.81 | DPP4 (0.55) | ITGB3ITGA2BDPP4DPP8DPP9 | |
| SCHEMBL2071701 | 0.80 | NOTUM (0.83) | NOTUMCYP2C19FFAR4PDK2SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311810-A1 | AMIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2011-04-20 | — | — | EP | disclosed |