Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6066623 | 0.91 | DPP4 (0.53) | DPP4DPP8DPP7DPP9ITGB3 | |
| Trifluoroacetic Acid SCHEMBL6066398 | 0.91 | DPP4 (0.53) | DPP4DPP8DPP7DPP9ITGB3 | |
| Trifluoroacetic Acid SCHEMBL1456260 | 0.91 | DPP4 (0.53) | DPP4DPP8DPP7DPP9ITGB3 | |
| SCHEMBL785766 | 0.87 | CHKA (0.50) | DPP4DPP8DPP7DPP9ITGB3 | |
| Hydrochloric Acid SCHEMBL2338735 | 0.86 | CHKA (0.48) | DPP4DPP8DPP7DPP9ITGB3 | |
| Trifluoroacetic Acid SCHEMBL1025272 | 0.85 | ITGB3 (0.59) | DPP4DPP8DPP7DPP9ITGB3 | |
| Trifluoroacetic Acid SCHEMBL1456945 | 0.83 | DPP4 (0.59) | DPP4DPP8DPP7DPP9ITGB3 | |
| Trifluoroacetic Acid SCHEMBL1648792 | 0.81 | ITGB3 (0.56) | DPP4DPP8DPP7DPP9ITGB3 | |
| Trifluoroacetic Acid SCHEMBL8120233 | 0.80 | DPP4 (0.45) | DPP4DPP8DPP7DPP9ITGB3 | |
| Trifluoroacetic Acid SCHEMBL8126751 | 0.79 | ADRB2 (0.48) | DPP4DPP8DPP7DPP9ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877401-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | Elan Pharmaceuticals Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2006113140-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | ELAN PHARMACEUTICALS, INC. (US) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | DPP4 2122/4885DPP8 1836/4885DPP7 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.