Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16488117 | 0.88 | ESR1 (0.46) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL13870910 | 0.85 | KDM4E (0.59) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL14500792 | 0.83 | KDM4E (0.59) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL16488115 | 0.83 | ESR1 (0.47) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL16487805 | 0.82 | SMN1; SMN2 (0.46) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL13870933 | 0.80 | ALDH1A1 (0.48) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL13870921 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL13870820 | 0.76 | KDM4E (0.49) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8261896 | 0.75 | SMN1; SMN2 (0.72) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL13870924 | 0.74 | SMN1; SMN2 (0.66) | TDO2SMN1; SMN2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8956737-B2 | Red phosphorescent compound and organic electroluminescent device using the same | LG DISPLAY CO., LTD. (KR) | 2015-02-17 | — | — | US | disclosed |