Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAC1 | P63000 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13870820 | 0.88 | KDM4E (0.49) | ESR1ESR2TDO2KDM4ESMN1; SMN2 | |
| SCHEMBL16488116 | 0.88 | TDO2 (0.49) | ESR1ESR2TDO2KDM4ESMN1; SMN2 | |
| SCHEMBL13870911 | 0.84 | KDM4E (0.56) | ESR1ESR2TDO2KDM4ESMN1; SMN2 | |
| SCHEMBL16488115 | 0.83 | ESR1 (0.47) | ESR1ESR2TDO2KDM4ESMN1; SMN2 | |
| SCHEMBL13647122 | 0.81 | KDM4E (0.55) | ESR1ESR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL16487804 | 0.81 | KDM4E (0.43) | ESR1ESR2TDO2KDM4ESMN1; SMN2 | |
| SCHEMBL13870932 | 0.78 | MAOA (0.44) | TDO2KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13870922 | 0.75 | ALDH1A1 (0.50) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL13647124 | 0.73 | KDM4E (0.57) | ESR1ESR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8261896 | 0.72 | SMN1; SMN2 (0.72) | ESR1ESR2TDO2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8956737-B2 | Red phosphorescent compound and organic electroluminescent device using the same | LG DISPLAY CO., LTD. (KR) | 2015-02-17 | — | — | US | disclosed |