Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855605 | 0.83 | NPSR1 (0.42) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL9500857 | 0.81 | ASAH1 (0.43) | LMNAALDH1A1HTR2A | |
| SCHEMBL10618424 | 0.78 | HPGD (0.52) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL27575979 | 0.78 | LMNA (0.45) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL5975716 | 0.77 | ADRA2A (0.46) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL16838683 | 0.77 | ADRA2A (0.46) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL8201163 | 0.77 | ADRA2A (0.46) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL1950755 | 0.77 | LMNA (0.43) | LMNAALDH1A1TAAR1HTR2A | |
| SCHEMBL8353716 | 0.77 | ALDH1A1 (0.49) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL10140605 | 0.77 | ALDH1A1 (0.49) | LMNAADRA2AADRA2CHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2837630-B1 | METHOD FOR SYNTHESIZING SAPROPTERIN DIHYDROCHLORIDE | ASYMCHEM LAB TIANJIN CO LTD (CN) | 2016-11-23 | — | — | EP | disclosed |
| EP-2837630-A1 | METHOD FOR SYNTHESIZING SAPROPTERIN DIHYDROCHLORIDE | Asymchem Laboratories (Tianjin) Co., Ltd (CN) | 2015-02-18 | — | — | EP | disclosed |