Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 3/20 | 0.52 |
| ▸ | CMA1 | P23946 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 7/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13287429 | 1.00 | CTSG (0.52) | CTSGCMA1MEN1KMT2ATAAR1 | |
| SCHEMBL1436847 | 0.87 | MME (0.58) | MEN1KMT2ATAAR1MMEACE | |
| SCHEMBL13857697 | 0.84 | CTSG (0.54) | CTSGCMA1ALDH1A1THRBCYP2C9 | |
| SCHEMBL22249863 | 0.82 | CTRB1 (0.53) | CTSGCMA1ALDH1A1THRBCYP2C9 | |
| SCHEMBL29045684 | 0.80 | MME (0.58) | MMEACECPA1ACE2MMP2 | |
| SCHEMBL29045685 | 0.80 | MME (0.58) | MMEACECPA1ACE2MMP2 | |
| SCHEMBL13494637 | 0.78 | MME (0.55) | MEN1KMT2ATAAR1MMEACE | |
| SCHEMBL14363442 | 0.78 | CTSG (0.62) | CTSGCMA1ALDH1A1ACE | |
| SCHEMBL14865867 | 0.78 | CTSG (0.62) | CTSGCMA1ALDH1A1ACE | |
| SCHEMBL6942656 | 0.77 | CTSG (0.65) | CTSGCMA1KMT2AALDH1A1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955233-A1 | Proteinase K inhibitors, methods and compositions therefor | Life Technologies Corporation (US) | 2015-12-16 | — | — | EP | disclosed |
| EP-2367954-B1 | PROTEINASE K INHIBITORS, METHODS AND COMPOSITIONS THEREFOR | LIFE TECHNOLOGIES CORP (US) | 2015-02-18 | — | — | EP | disclosed |