Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21563123 | 0.82 | APLNR (0.37) | — | |
| SCHEMBL16489098 | 0.82 | APLNR (0.37) | — | |
| SCHEMBL16489101 | 0.77 | — | — | |
| SCHEMBL24961660 | 0.71 | OPRM1 (0.34) | — | |
| SCHEMBL15308692 | 0.71 | OPRM1 (0.34) | — | |
| SCHEMBL16271221 | 0.70 | HTT (0.30) | HTT | |
| SCHEMBL4547463 | 0.70 | HTT (0.30) | HTT | |
| SCHEMBL27383982 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL16489097 | 0.69 | — | — | |
| SCHEMBL21738973 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493438-B2 | 4,4-difluoro-piperidine-compounds | ROTTAPHARM S.R.L. (IT) | 2016-11-15 | — | — | US | disclosed |
| US-20150051226-A1 | 4,4-DIFLUORO-PIPERIDINE-COMPOUNDS | ROTTAPHARM S.P.A. (IT) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051226-A1 | 4,4-DIFLUORO-PIPERIDINE-COMPOUNDS | SLCO4C1, PAICS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | HTT 2527/4885NCF1 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.