Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | HINT1 | P49773 | 3/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21778179 | 1.00 | KDM4E (0.56) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL16844109 | 0.88 | POLB (0.51) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL4578872 | 0.88 | POLB (0.51) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL12570242 | 0.88 | POLB (0.51) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL1514931 | 0.88 | POLB (0.51) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL7613803 | 0.88 | POLB (0.51) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL21538191 | 0.88 | POLB (0.48) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL427928 | 0.87 | POLB (0.48) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL887469 | 0.87 | POLB (0.48) | KDM4EPOLBP2RY2P2RY4P2RY6 | |
| SCHEMBL427927 | 0.87 | POLB (0.48) | KDM4EPOLBP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932623-B2 | Nucleotide analogs | ABBOTT MOLECULAR INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-9932623-B2 | Nucleotide analogs | ABBOTT MOLECULAR INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-20150050697-A1 | NUCLEOTIDE ANALOGS | ABBOTT MOLECULAR INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150050697-A1 | NUCLEOTIDE ANALOGS | ABBOTT MOLECULAR INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150051113-A1 | NUCLEOTIDE ANALOGS | ABBOTT MOLECULAR INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150051113-A1 | NUCLEOTIDE ANALOGS | ABBOTT MOLECULAR INC. | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150050697-A1 | NUCLEOTIDE ANALOGS | NUDT1, NT5C3B, RNGTT | KDM4E 4150/4885POLB 32/4885P2RY2 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.