Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | PDE6D | O43924 | 1/20 | 0.56 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.56 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | BRD4 | O60885 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16489685 | 0.84 | BRD4 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL16489620 | 0.83 | ALDH1A1 (0.56) | ALDH1A1PDE6DALDH2ALDH3A1MAPT | |
| SCHEMBL16489709 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PDE6DALDH2ALDH3A1MAPT | |
| SCHEMBL16489605 | 0.81 | BRD4 (0.59) | BRD4 | |
| SCHEMBL16489711 | 0.81 | ALDH1A1 (0.50) | ALDH1A1PDE6DALDH2ALDH3A1MAPT | |
| SCHEMBL16489606 | 0.80 | BRD4 (0.60) | BRD4 | |
| SCHEMBL16489616 | 0.80 | ALDH1A1 (0.54) | ALDH1A1PDE6DALDH2ALDH3A1MAPT | |
| SCHEMBL16489617 | 0.79 | ALDH1A1 (0.57) | ALDH1A1PDE6DALDH2ALDH3A1MAPT | |
| SCHEMBL16489684 | 0.76 | BRD4 (0.58) | ALDH1A1KDM4EBRD4CYP1A2CYP2C9 | |
| SCHEMBL16489621 | 0.75 | ALDH1A1 (0.54) | ALDH1A1PDE6DALDH2ALDH3A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246919-A1 | PYRIDINONES | BOEHRINGER INGELHEIM INT (DE) | 2015-09-03 | — | — | US | disclosed |
| US-20150051208-A1 | PYRIDINONES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051208-A1 | PYRIDINONES | MKI67, XDH, CDK6 | ALDH1A1 545/4885PDE6D 297/4885ALDH2 1425/4885 |
| US-20150246919-A1 | PYRIDINONES | MKI67, XDH, CDK6 | ALDH1A1 545/4885PDE6D 297/4885ALDH2 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.