SCHEMBL16492000

SCHEMBL16492000

CCCCc1ccc(N(c2ccc(/C=C/c3ccc(N(c4ccc(C)cc4)c4ccc(OC)cc4)cc3)cc2)c2ccc(/C=C/c3ccc(N(c4ccc(C)cc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.57
ALDH1A1 P00352 3/20 0.46
AHR P35869 1/20 0.46
MAPT P10636 2/20 0.43
LMNA P02545 3/20 0.43
GAA P10253 2/20 0.43
MEN1 O00255 1/20 0.43
HPGD P15428 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CALM1 P0DP23 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16489731 1.00 RELA (0.57) RELAALDH1A1AHRMAPTLMNA
SCHEMBL16489741 1.00 RELA (0.57) RELAALDH1A1AHRMAPTLMNA
SCHEMBL5608630 0.92 MAPT (0.50) ALDH1A1MAPTLMNAGAAMEN1
SCHEMBL16922637 0.91 RELA (0.47) RELAALDH1A1AHRMAPTLMNA
SCHEMBL14200071 0.90 CYP3A4 (0.44) LMNAHPGDTP53CYP3A4CYP1A2
SCHEMBL16489729 0.90 CYP3A4 (0.44) LMNAHPGDTP53CYP3A4CYP1A2
SCHEMBL16489750 0.90 CYP3A4 (0.44) LMNAHPGDTP53CYP3A4CYP1A2
SCHEMBL12593363 0.90 CYP3A4 (0.44) LMNAHPGDTP53CYP3A4CYP1A2
SCHEMBL15496839 0.88 RELA (0.55) RELAALDH1A1MAPTLMNAMEN1
SCHEMBL13996325 0.87 AHR (0.57) RELAALDH1A1AHRMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220197162-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2022-06-23 US disclosed
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-20190346779-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2019-11-14 US disclosed
US-9791791-B2 Electrophotographic photoreceptor, electrophotographic cartridge, image forming apparatus, and charge transport substance MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-17 US disclosed
US-20160320717-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC CARTRIDGE, IMAGE FORMING APPARATUS, AND CHARGE TRANSPORT SUBSTANCE MITSUBISHI CHEMICAL CORPORATION (JP) 2016-11-03 US disclosed
US-9400438-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2016-07-26 US disclosed
US-20160018746-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMATION DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2016-01-21 US disclosed
US-20150212436-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2015-07-30 US disclosed
US-20150050589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2015-02-19 US disclosed