Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943791 | 0.93 | CALM1 (0.55) | MAPTLMNAGAAALDH1A1MEN1 | |
| SCHEMBL16492000 | 0.92 | RELA (0.57) | MAPTLMNAGAAALDH1A1MEN1 | |
| SCHEMBL16489741 | 0.92 | RELA (0.57) | MAPTLMNAGAAALDH1A1MEN1 | |
| SCHEMBL16489731 | 0.92 | RELA (0.57) | MAPTLMNAGAAALDH1A1MEN1 | |
| SCHEMBL12313741 | 0.88 | CA2 (0.52) | LMNAALDH1A1HPGDSMN1; SMN2ACHE | |
| SCHEMBL12313686 | 0.88 | CA2 (0.52) | LMNAALDH1A1HPGDSMN1; SMN2ACHE | |
| SCHEMBL12313679 | 0.88 | CA2 (0.52) | LMNAALDH1A1HPGDSMN1; SMN2ACHE | |
| SCHEMBL12593396 | 0.88 | CA2 (0.52) | LMNAALDH1A1HPGDSMN1; SMN2ACHE | |
| SCHEMBL4570447 | 0.88 | CA2 (0.52) | LMNAALDH1A1HPGDSMN1; SMN2ACHE | |
| SCHEMBL12313700 | 0.88 | CA2 (0.52) | LMNAALDH1A1HPGDSMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354887-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1097158-B1 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-01-25 | — | — | EP | disclosed |