SCHEMBL16492018

SCHEMBL16492018

CCc1ccc(C(=O)NN)s1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.59
RAB9A P51151 5/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
NPC1 O15118 4/20 0.58
HPGD P15428 3/20 0.58
TSHR P16473 2/20 0.58
TP53 P04637 1/20 0.58
KMT2A Q03164 4/20 0.54
ALDH1A1 P00352 5/20 0.51
MAPT P10636 3/20 0.51
KDM4E B2RXH2 2/20 0.51
POLB P06746 2/20 0.51
MEN1 O00255 3/20 0.49
GAA P10253 2/20 0.49
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
AOC3 Q16853 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12181191 0.85 RAB9A (0.58) SMYD3RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL11984356 0.84 RAB9A (0.57) SMYD3RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL12313374 0.83 RAB9A (0.63) SMYD3RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL8627366 0.82 SMYD3 (0.54) SMYD3RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL276955 0.81 ALDH1A1 (0.58) KMT2AALDH1A1MAPTKDM4EPOLB
SCHEMBL12313385 0.80 RAB9A (0.60) SMYD3RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL27336171 0.80 RAB9A (0.54) SMYD3RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL27779290 0.80 ALDH1A1 (0.56) SMYD3RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL2225204 0.80 HPGD (0.54) SMYD3RAB9ASMN1; SMN2NPC1HPGD
SCHEMBL27981316 0.79 HPGD (0.58) SMYD3RAB9ASMN1; SMN2NPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023127507-A1 POWDERED PIGMENT COMPOSITION, METHOD FOR PRODUCING POWDERED PIGMENT COMPOSITION, RESIN COMPOSITION, AND MOLDED BODY DIC株式会社 2023-07-06 WO disclosed
EP-3059288-B1 RESIN COMPOSITION AND MOLDED ARTICLE DAINIPPON INK & CHEMICALS (JP) 2021-12-22 EP disclosed
US-20210030895-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2021-02-04 US disclosed
US-20210024821-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2021-01-28 US disclosed
US-20210024821-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2021-01-28 US disclosed
EP-3034580-B1 RESIN COMPOSITION AND MOLDED ARTICLE DAINIPPON INK & CHEMICALS (JP) 2020-04-29 EP disclosed
US-20160271273-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2016-09-22 US disclosed
US-20160271273-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2016-09-22 US disclosed
US-20160271273-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC CORPORATION (JP) 2016-09-22 US disclosed
WO-2016132597-A1 RESIN COMPOSITION AND MOLDED BODY DIC株式会社 2016-08-25 WO disclosed
EP-3059288-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC Corporation (JP) 2016-08-24 EP disclosed
US-20160200970-A1 RESIN COMPOSITION AND MOLDED ARTICLE NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) 2016-07-14 US disclosed
US-20160200970-A1 RESIN COMPOSITION AND MOLDED ARTICLE NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) 2016-07-14 US disclosed
US-20160200970-A1 RESIN COMPOSITION AND MOLDED ARTICLE NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) 2016-07-14 US disclosed
EP-3034580-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC Corporation (JP) 2016-06-22 EP disclosed
WO-2015022977-A1 RESIN COMPOSITION AND MOLDED ARTICLE DIC株式会社 (JP) 2015-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160271273-A1 RESIN COMPOSITION AND MOLDED ARTICLE IK, CBR3, RER1 SMYD3 2316/4885RAB9A 1499/4885SMN1; SMN2 3305/4885
US-20210030895-A1 RESIN COMPOSITION AND MOLDED ARTICLE IK, CBR3, RER1 SMYD3 2316/4885RAB9A 1499/4885SMN1; SMN2 3305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.