Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.44 |
| ▸ | TEK | Q02763 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9143504 | 0.89 | KDR (0.50) | KDM4EMAPTKDREPHB4TEK | |
| Ammonia Solution, Strong SCHEMBL28862432 | 0.88 | KDR (0.49) | KDM4EMAPTKDREPHB4TEK | |
| SCHEMBL28367077 | 0.73 | GSK3B (0.36) | KDM4EKDREPHB4TEKFLT3 | |
| SCHEMBL2682667 | 0.73 | PTGS2 (0.49) | KDM4EFLT3NPC1RAB9APTGS2 | |
| SCHEMBL26098876 | 0.73 | PTGS2 (0.49) | KDM4EMAPTKDREPHB4TEK | |
| SCHEMBL5049519 | 0.73 | NPC1 (0.42) | KDM4EMAPTKDREPHB4TEK | |
| SCHEMBL14446422 | 0.73 | KDR (0.52) | KDREPHB4TEKHDAC3HDAC4 | |
| SCHEMBL15426810 | 0.73 | KEAP1 (0.55) | KDM4ECYP3A4MAPTNPC1RAB9A | |
| SCHEMBL28298649 | 0.73 | HSD17B1 (0.50) | KDM4EMAPTNPC1RAB9AMEN1 | |
| SCHEMBL2687071 | 0.72 | KMT2A (0.52) | KDREPHB4HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015022335-A1 | VANCOMYCIN ANALOGS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2015-02-19 | — | — | WO | disclosed |